Induced pluripotent stem (iPS) cells are laboratory-produced cells that combine the advantages of biological and adult somatic stem cells for cell-based therapies. The reprogramming of cells, such as fibroblasts, into embryonic stem cell-like state is done by ectopic expression of transcription factor is responsible for generating embryonic stem cell properties.

This primer factor is octamer – bind transcription factor 4 (Oct3 / 4 ), sex determining region Y-box 2 (Sox2), Krüppel like factor 4 (Klf 4 ), and the proto-oncogene homolog protein from bird myelocytomatosis (c-Myc). Somatic cells can be easily obtained from the patient to be subjected to cell therapy and reprogrammed to obtain necessary high plasticity of embryonic stem cells.

These cells have no ethical limitations were involved, as in the case of embryonic stem cells, and displays minimal risk of immunologic rejection after transplantation. Currently, several ongoing clinical trials, most of them in Phase I or II. However, some of the inherent risks, such as chromosomal instability, insertional tumor, and teratoma formation, must be overcome to achieve full clinical translation. However, clinical trials and extensive basic research studying the biology of these cells, a promising future for the human cell-based therapy using iPS cells seem to be more clear and close.

Induced Pluripotent Stem Cells: Hope in the Treatment of Diseases, including Muscular Dystrophies
Induced Pluripotent Stem Cells: Hope in the Treatment of Diseases, including Muscular Dystrophies

Dexamethasone inhibits stemness Improving maintenance and chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation HIF-1α and Oct4

It has been controversial whether patients with hepatocellular carcinoma (HCC) should receive glucocorticoid therapy during chemotherapy. Recent studies have shown that glucocorticoids increase the sensitivity of tumor therapy for some chemotherapy drugs, but the specific mechanism remains unclear. In this study, dexamethasone (Dex) is used for stem cells to treat HCC. The results showed that Dex reduced maintenance stemness and self-renewal of cells HCC stem, promoted the epithelial-to-mesenchymal transition, migration inhibiting and angiogenesis and, more importantly, increase the sensitivity of cells to herpes simplex virus thymidine kinase / ganciclovir system of medicine in vitro and in vivo.

Further mechanistic analysis showed that Dex inhibits small ubiquitin-like modifier (SUMO) modification of some proteins in HCC stem cells, including hypoxia inducible factor (HIF) -1α, protein hypoxia tolerance is important, and octamer – bind transcription factor 4 (October 4 ), stemness protein essential maintenance. DeSUMOylation encourage HIF-1α and October 4 reduced their accumulation in the nucleus, thereby inhibiting tumor angiogenesis and maintenance of stemness.

This finding provides a new perspective to study the mechanisms underlying the effects of anti-hepatocarcinogenesis of Dex. Because of the side effects of glucocorticoids on low-dose anti-inflammatory effect, the right combination of glucocorticoids and chemotherapy drugs are expected to improve the survival of HCC patients and their prognosis.Androgen deprivation therapy eventually lead to the development castration- resistant prostate cancer (CRPC)

CF568 donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20105
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20106
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 rabbit anti-goat IgG(H+L)

9-20107
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 goat anti-guinea pig IgG(H+L)

9-20108
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-mouse IgG(H+L)

9-20110
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20111
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rabbit IgG(H+L)

9-20112
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20113
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20114
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20115
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20116
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-goat IgG(H+L)

9-20117
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-guinea pig IgG(H+L)

9-20118
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-mouse IgG(H+L)

9-20120
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20121
  • EUR 319.20
  • EUR 326.40
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rabbit IgG(H+L)

9-20122
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20123
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20124
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20125
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20126
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20127
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-goat IgG(H+L)

9-20128
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-guinea pig IgG(H+L)

9-20129
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-human IgG(H+L), highly cross-adsorbed

9-20132
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20133
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20134
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-rat IgG(H+L), highly cross-adsorbed

9-20135
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20136
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-rat IgG(H+L), highly cross-adsorbed

9-20137
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-swine IgG(H+L)

9-20138
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-mouse IgG(H+L)

9-20140
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rabbit IgG(H+L)

9-20141
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20142
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20143
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20144
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20147
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20148
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20149
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20152
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-human IgG(H+L), highly cross-adsorbed

9-20154
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20155
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20156
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-rat IgG(H+L), highly cross-adsorbed

9-20157
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20158
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-rat IgG(H+L), highly cross-adsorbed

9-20159
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-swine IgG(H+L)

9-20160
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-chicken IgY ( IgG) (H+L)

9-20164
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-chicken IgY (IgG) (H+L)

9-20165
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20166
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20167
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20168
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A donkey anti-guinea pig IgG(H+L), highly cross-adsorbed

9-20169
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed

9-20170
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed

9-20171
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A rabbit anti-sheep IgG(H+L), highly cross-adsorbed

9-20172
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed

9-20173
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed

9-20174
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20175
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20176
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20177
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20178
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20179
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-mouse IgG(H+L)

9-20180
  • EUR 271.20
  • EUR 277.20
  • 0.5 mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-rabbit IgG(H+L)

9-20181
  • EUR 271.20
  • EUR 277.20
  • 0.5 mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20182
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-mouse IgG(H+L)

9-20183
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20184
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-rabbit IgG(H+L)

9-20185
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20186
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20189
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20190
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20191
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-mouse IgG(H+L)

9-20197
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-guinea pig IgG(H+L)

9-20198
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-rat IgG(H+L), highly cross-adsorbed

9-20199
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R rabbit anti-mouseIgG(H+L), highly cross-adsorbed

9-20200
  • EUR 283.20
  • EUR 290.40
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R rabbit anti-rat IgG(H+L), highly cross-adsorbed

9-20201
  • EUR 283.20
  • EUR 290.40
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-rabbit IgG(H+L)

9-20202
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-mouse IgG(H+L)

9-20208
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-rabbit IgG(H+L)

9-20209
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-mouse IgG(H+L)

9-20221
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-mouse IgG(H+L)

9-20222
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-rabbit IgG(H+L)

9-20223
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-rabbit IgG(H+L)

9-20224
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-goat IgG(H+L)

9-20225
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-goat IgG(H+L)

9-20226
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-goat IgG(H+L)

9-20227
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-human IgG(H+L), highly cross-adsorbed

9-20230
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20231
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20232
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20233
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20234
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20235
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-swine IgG(H+L)

9-20236
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF680 rabbit anti-guinea pig IgG(H+L)

9-20243
  • EUR 306.00
  • EUR 312.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF770 rabbit anti-guinea pig IgG(H+L)

9-20244
  • EUR 306.00
  • EUR 312.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20275
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed

9-20276
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-human IgG(H+L), highly cross-adsorbed

9-20280
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-mouse IgG(H+L), highly cross-adsorbed

9-20281
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-rabbit IgG(H+L), highly cross-adsorbed

9-20282
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20283
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20284
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20285
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-swine IgG(H+L)

9-20286
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20293
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20294
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20295
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20296
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20297
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed

9-20299
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-rabbit IgG (H+L), highly cross-adsorbed

9-20300
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)

9-20301
  • EUR 388.80
  • EUR 396.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)

9-20302
  • EUR 388.80
  • EUR 396.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)

9-20303
  • EUR 388.80
  • EUR 396.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)

9-20304
  • EUR 388.80
  • EUR 396.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20305
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-mouse IgG(H+L)

9-20306
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Rabbit anti-mouse IgG(H+L), highly cross-adsorbed

9-20307
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20308
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-rabbit IgG(H+L)

9-20309
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed

9-20310
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-chicken IgY(H+L), highly cross-adsorbed

9-20311
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-chicken IgY (IgG) (H+L)

9-20312
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Bovine anti-goat IgG(H+L), highly cross-adsorbed

9-20313
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-goat IgG(H+L), highly cross-adsorbed

9-20314
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-goat IgG(H+L)

9-20315
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed

9-20316
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-guinea pig IgG(H+L)

9-20317
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-human IgG(H+L), highly cross-adsorbed

9-20318
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-human IgG(H+L), highly cross-adsorbed

9-20319
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-rat IgG(H+L), highly cross-adsorbed

9-20320
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-rat IgG(H+L), highly cross-adsorbed

9-20321
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-sheep IgG(H+L), highly cross-adsorbed

9-20322
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-sheep IgG(H+L), highly cross-adsorbed

9-20323
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-swine IgG(H+L)

9-20324
  • EUR 271.20
  • EUR 277.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)

9-20328
  • EUR 388.80
  • EUR 396.00
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 Chicken Anti-Mouse IgG(H+L), 2 mg/mL

9-20331
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF350 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL

9-20332
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Goat IgG(H+L), 2 mg/mL

9-20333
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Mouse IgG(H+L), 2 mg/mL

9-20334
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL

9-20335
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Rabbit Anit-Guinea Pig IgG(H+L), 2 mg/mL

9-20336
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Goat IgG(H+L), 2 mg/mL

9-20337
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Mouse IgG(H+L), 2 mg/mL

9-20338
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL

9-20339
  • EUR 277.20
  • EUR 271.20
  • EUR 144.00
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL

9-20340
  • EUR 396.00
  • EUR 388.80
  • EUR 164.40
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF633 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL

9-20341
  • EUR 396.00
  • EUR 388.80
  • EUR 164.40
  • 1mg
  • 0.5mL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF647 Goat Anti-Human IgM (mu chain), 2mg/mL

9-20346
  • EUR 248.40
  • EUR 164.40
  • 250uL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF488A Goat Anti-Human IgM (mu chain), 2mg/mL

9-20347
  • EUR 248.40
  • EUR 164.40
  • 250uL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF594 Goat Anti-Human IgM (mu chain), 2mg/mL

9-20348
  • EUR 248.40
  • EUR 164.40
  • 250uL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF640R Goat Anti-Human IgM (mu chain), 2mg/mL

9-20349
  • EUR 248.40
  • EUR 164.40
  • 250uL
  • 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF350 Donkey anti-mouse IgG(H+L), highly cross-adsorbed

9-20350
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed

9-20351
  • EUR 312.00
  • EUR 319.20
  • 0.5mL
  • 1mg
Description: Minimum order quantity: 1 unit of 1mg

R-phycoerythrin goat anti-mouse IgG(H+L), 0.5 mg/mL

9-20352
  • EUR 374.40
  • EUR 178.80
  • 1mL
  • 200uL
Description: Minimum order quantity: 1 unit of 200uL

R-phycoerythrin goat anti-rabbit IgG(H+L), 0.5 mg/mL

9-20353
  • EUR 374.40
  • EUR 178.80
  • 1mL
  • 200uL
Description: Minimum order quantity: 1 unit of 200uL

Here, we demonstrate for the first time that histone H3K 4 SETD1A methyltransferase is the main regulator of the proliferation of metastatic CRPC (mCRPC). SETD1A expression was significantly correlated with survival rate of patients with prostate cancer.