Proangiogenic Hypoxia-Mimicking Agents Attenuate Osteogenic Potential of Adipose Stem/Stromal Cells

Background: inhibits vascularization of bone tissue engineering strategies are not enough to reconstruct large bone defects. Delivery prolyl hydroxylase inhibitor (restricted) is an interesting approach to upregulate vascular endothelial growth factor (VEGF) by imitating the stabilization of hypoxia hypoxia-inducible factor-1 alpha (HIF-1α). The study assessed the two is limited to: dimethyloxalylglycine (DMOG) and baicalein for their effect on human adipose tissue-derived mesenchymal stem / stromal cells (AT-MSCs).

Method: Isolated AT-MSCs were marked and treated is limited to cell proliferation response rate. Immunostaining and Western-spotting duty to verify the stabilization of HIF-1α response. concentration that is optimized for long-term treatment were tested for their effect on the cell cycle, apoptosis, cytokine secretion, and osteogenic differentiation of AT-MSCs.

the level of gene expression is evaluated for alkaline phosphatase (Alpl), bone morphogenetic protein 2 (BMP2), dwarf related to transcription factor 2 (Runx2), vascular endothelial growth factor A (VEGFA), secreted phosphoprotein 1 (SPP1), and collagen type I alpha 1 (COL1A1). Additionally, genes associated stemness-Kruppel-like factor 4 (KLF 4 ), Nanog homeobox (NANOG), and octamer < / em> – bind transcription factor 4 (OCT 4 ) rated.

Results: The restricted stabilized HIF-1α in a dose-dependent manner and showed a clear dose and time-dependent antiproliferative effect. At a dose of maintaining proliferation, reduced baicalein DMOG and osteogenic induction effect on the expression of Runx2, Alpl, and COL1A1, and is able to suppress the formation of a mineral matrix. Pressed osteogenic response of AT-MSCs accompanied by upregulation of genes associated with stemness.

Conclusion: This is restricted significantly reduced osteogenic differentiation of AT-MSCs and genes associated with stemness somewhat regulated. This restricted proangiogenic potential must be weighed against the long-term of their direct inhibitory effect on osteogenic differentiation of AT-MSCs.

A three-gene signature may predict prognosis in patients with acute myeloid leukemia Identification of an effective signature is crucial for predicting the prognosis of acute myeloid leukemia (AML).

The investigation aims to identify new signature for AML predictive prognostic using the expression of three genes ( octamer – bind transcription factor 4 (OCT 4 ), POU domain type 5 transcription factor 1B (POU5F1B) and cell-specific B- murine leukemia integration of virus Moloney site-1 pseudogene 1 (BMI1P1), the expression of genes derived from our previous study. Only specimens in which three genes all expressed were included in this study.

A signature three genes are constructed by Cox multivariate regression for the patients were divided be a high-risk group and low-risk Receiver operating characteristic (ROC) analysis of three-gene signature (area under the ROC curve (AUC) = 0.901, 95% CI :. 0.821- 0.981, P <0.001) indicates that it is a signature more valuable to differentiate between patients and controls from one of the three genes, in addition, cell white blood-cells (leukocytes, P = 0.00 4 ), pl atelets (PLTS, P = 0.017), the percentage of blasts in the bone marrow (BM) (P = 0.011) and complete remission (CR, P = 0.027) had a significant difference between the two groups.

CF568 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20103	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20104	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20105	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20106	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 rabbit anti-goat IgG(H+L)
9-20107	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 goat anti-guinea pig IgG(H+L)
9-20108	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-mouse IgG(H+L)
9-20110	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20111	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rabbit IgG(H+L)
9-20112	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20113	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20114	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20115	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20116	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-goat IgG(H+L)
9-20117	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-guinea pig IgG(H+L)
9-20118	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-mouse IgG(H+L)
9-20120	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20121	Biotium	EUR 319.20 EUR 326.40	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rabbit IgG(H+L)
9-20122	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20123	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20124	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20125	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20126	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20127	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-goat IgG(H+L)
9-20128	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-guinea pig IgG(H+L)
9-20129	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-human IgG(H+L), highly cross-adsorbed
9-20132	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20133	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20134	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-rat IgG(H+L), highly cross-adsorbed
9-20135	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20136	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-rat IgG(H+L), highly cross-adsorbed
9-20137	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 goat anti-swine IgG(H+L)
9-20138	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-mouse IgG(H+L)
9-20140	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rabbit IgG(H+L)
9-20141	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20142	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20143	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20144	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20147	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20148	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20149	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20152	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-human IgG(H+L), highly cross-adsorbed
9-20154	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20155	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20156	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-rat IgG(H+L), highly cross-adsorbed
9-20157	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20158	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-rat IgG(H+L), highly cross-adsorbed
9-20159	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 goat anti-swine IgG(H+L)
9-20160	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-chicken IgY ( IgG) (H+L)
9-20164	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 rabbit anti-chicken IgY (IgG) (H+L)
9-20165	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20166	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20167	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20168	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A donkey anti-guinea pig IgG(H+L), highly cross-adsorbed
9-20169	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed
9-20170	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 donkey anti-guinea pig IgG(H+L), highly cross-adsorbed
9-20171	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A rabbit anti-sheep IgG(H+L), highly cross-adsorbed
9-20172	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed
9-20173	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 rabbit anti-sheep IgG(H+L), highly cross-adsorbed
9-20174	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20175	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20176	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20177	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20178	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20179	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-mouse IgG(H+L)
9-20180	Biotium	EUR 271.20 EUR 277.20	0.5 mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-rabbit IgG(H+L)
9-20181	Biotium	EUR 271.20 EUR 277.20	0.5 mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF405M goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20182	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-mouse IgG(H+L)
9-20183	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20184	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-rabbit IgG(H+L)
9-20185	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20186	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20189	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20190	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

Biotin donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20191	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-mouse IgG(H+L)
9-20197	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 goat anti-guinea pig IgG(H+L)
9-20198	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R donkey anti-rat IgG(H+L), highly cross-adsorbed
9-20199	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R rabbit anti-mouseIgG(H+L), highly cross-adsorbed
9-20200	Biotium	EUR 283.20 EUR 290.40	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R rabbit anti-rat IgG(H+L), highly cross-adsorbed
9-20201	Biotium	EUR 283.20 EUR 290.40	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R goat anti-rabbit IgG(H+L)
9-20202	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-mouse IgG(H+L)
9-20208	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-rabbit IgG(H+L)
9-20209	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-mouse IgG(H+L)
9-20221	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-mouse IgG(H+L)
9-20222	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-rabbit IgG(H+L)
9-20223	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-rabbit IgG(H+L)
9-20224	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A chicken anti-goat IgG(H+L)
9-20225	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 chicken anti-goat IgG(H+L)
9-20226	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 chicken anti-goat IgG(H+L)
9-20227	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-human IgG(H+L), highly cross-adsorbed
9-20230	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20231	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20232	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20233	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20234	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20235	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 goat anti-swine IgG(H+L)
9-20236	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF680 rabbit anti-guinea pig IgG(H+L)
9-20243	Biotium	EUR 306.00 EUR 312.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF770 rabbit anti-guinea pig IgG(H+L)
9-20244	Biotium	EUR 306.00 EUR 312.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20275	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF555 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed
9-20276	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-human IgG(H+L), highly cross-adsorbed
9-20280	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-mouse IgG(H+L), highly cross-adsorbed
9-20281	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-rabbit IgG(H+L), highly cross-adsorbed
9-20282	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20283	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20284	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20285	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF647 goat anti-swine IgG(H+L)
9-20286	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20293	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20294	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20295	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF633 Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20296	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20297	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed
9-20299	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-rabbit IgG (H+L), highly cross-adsorbed
9-20300	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF568 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)
9-20301	Biotium	EUR 388.80 EUR 396.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF488A Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)
9-20302	Biotium	EUR 388.80 EUR 396.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF594 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)
9-20303	Biotium	EUR 388.80 EUR 396.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF640R Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)
9-20304	Biotium	EUR 388.80 EUR 396.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20305	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-mouse IgG(H+L)
9-20306	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Rabbit anti-mouse IgG(H+L), highly cross-adsorbed
9-20307	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20308	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-rabbit IgG(H+L)
9-20309	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-chicken IgY (IgG) (H+L), highly cross-adsorbed
9-20310	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-chicken IgY(H+L), highly cross-adsorbed
9-20311	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-chicken IgY (IgG) (H+L)
9-20312	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Bovine anti-goat IgG(H+L), highly cross-adsorbed
9-20313	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Donkey anti-goat IgG(H+L), highly cross-adsorbed
9-20314	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-goat IgG(H+L)
9-20315	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-guinea pig IgG (H+L), highly cross-adsorbed
9-20316	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-guinea pig IgG(H+L)
9-20317	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-human IgG(H+L), highly cross-adsorbed
9-20318	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-human IgG(H+L), highly cross-adsorbed
9-20319	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-rat IgG(H+L), highly cross-adsorbed
9-20320	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-rat IgG(H+L), highly cross-adsorbed
9-20321	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 donkey anti-sheep IgG(H+L), highly cross-adsorbed
9-20322	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 rabbit anti-sheep IgG(H+L), highly cross-adsorbed
9-20323	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 goat anti-swine IgG(H+L)
9-20324	Biotium	EUR 271.20 EUR 277.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF543 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat)
9-20328	Biotium	EUR 388.80 EUR 396.00	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 Chicken Anti-Mouse IgG(H+L), 2 mg/mL
9-20331	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF350 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL
9-20332	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Goat IgG(H+L), 2 mg/mL
9-20333	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Mouse IgG(H+L), 2 mg/mL
9-20334	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL
9-20335	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF543 Rabbit Anit-Guinea Pig IgG(H+L), 2 mg/mL
9-20336	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Goat IgG(H+L), 2 mg/mL
9-20337	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Mouse IgG(H+L), 2 mg/mL
9-20338	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Chicken Anti-Rabbit IgG(H+L), 2 mg/mL
9-20339	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL
9-20340	Biotium	EUR 396.00 EUR 388.80 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF633 Goat anti-mouse IgG (H+L), highly cross-adsorbed (min X Rat), 2 mg/mL
9-20341	Biotium	EUR 396.00 EUR 388.80 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF647 Goat Anti-Human IgM (mu chain), 2mg/mL
9-20346	Biotium	EUR 248.40 EUR 164.40	250uL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF488A Goat Anti-Human IgM (mu chain), 2mg/mL
9-20347	Biotium	EUR 248.40 EUR 164.40	250uL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF594 Goat Anti-Human IgM (mu chain), 2mg/mL
9-20348	Biotium	EUR 248.40 EUR 164.40	250uL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF640R Goat Anti-Human IgM (mu chain), 2mg/mL
9-20349	Biotium	EUR 248.40 EUR 164.40	250uL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF350 Donkey anti-mouse IgG(H+L), highly cross-adsorbed
9-20350	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

CF350 Donkey anti-rabbit IgG(H+L), highly cross-adsorbed
9-20351	Biotium	EUR 312.00 EUR 319.20	0.5mL 1mg
Description: Minimum order quantity: 1 unit of 1mg

R-phycoerythrin goat anti-mouse IgG(H+L), 0.5 mg/mL
9-20352	Biotium	EUR 374.40 EUR 178.80	1mL 200uL
Description: Minimum order quantity: 1 unit of 200uL

R-phycoerythrin goat anti-rabbit IgG(H+L), 0.5 mg/mL
9-20353	Biotium	EUR 374.40 EUR 178.80	1mL 200uL
Description: Minimum order quantity: 1 unit of 200uL

R-phycoerythrin goat anti-rat IgG(H+L), highly cross-adsorbed, 0.5 mg/mL
9-20354	Biotium	EUR 410.40 EUR 193.20	1mL 200uL
Description: Minimum order quantity: 1 unit of 200uL

R-phycoerythrin goat anti-human IgG(H+L), highly cross-adsorbed, 0.5 mg/mL
9-20355	Biotium	EUR 410.40 EUR 193.20	1mL 200uL
Description: Minimum order quantity: 1 unit of 200uL

CF405S Donkey anti-guinea pig IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20356	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

R-phycoerythrin F(ab')2 fragment of goat anti-mouse IgG(H+L), 0.5 mg/mL
9-20357	Biotium	EUR 178.80 EUR 410.40	200uL 500uL
Description: Minimum order quantity: 1 unit of 500uL

R-phycoerythrin F(ab')2 fragment of goat anti-rabbit IgG(H+L), 0.5 mg/mL
9-20358	Biotium	EUR 178.80 EUR 410.40	200uL 500uL
Description: Minimum order quantity: 1 unit of 500uL

CF350 Donkey anti-rat IgG(H+L), highly crossed-adsorbed, 2 mg/mL
9-20361	Biotium	EUR 290.40 EUR 283.20 EUR 150.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF750 Donkey anti-goat IgG(H+L), highly crossed-adsorbed, 2 mg/mL
9-20362	Biotium	EUR 312.00 EUR 164.40	0.25mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF350 Chicken Anti-Goat IgG(H+L), 2 mg/mL
9-20364	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF532 Goat Anti-Mouse IgG(H+L), 2 mg/mL
9-20365	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF532 Goat Anti-Rabbit IgG(H+L), 2 mg/mL
9-20366	Biotium	EUR 277.20 EUR 271.20 EUR 144.00	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF770 monoclonal mouse anti-biotin IgG, 2 mg/mL
9-20367	Biotium	EUR 339.60 EUR 193.20	250uL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF660C Goat anti-mouse IgG(H+L), highly cross-adsorbed (min X Rat), 2 mg/mL
9-20368	Biotium	EUR 396.00 EUR 388.80 EUR 199.20	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF660C Goat anti-rabbit IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20369	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF660C Goat anti-rat IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20370	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF660C Goat anti-chicken IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20371	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF660C Donkey Anti-Guinea Pig IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20372	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Goat anti-rabbit IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20373	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Goat anti-rat IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20374	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Goat anti-chicken IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20375	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405M Donkey Anti-Guinea Pig IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20376	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF568 Donkey Anti-Guinea Pig IgG(H+L), highly cross-adsorbed, 2 mg/mL
9-20377	Biotium	EUR 319.20 EUR 312.00 EUR 164.40	1mg 0.5mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

CF405S Goat Anti-Mouse IgG1 (γ1), 2mg/mL
9-20380	Biotium	EUR 332.40 EUR 178.80	0.25mL 50uL
Description: Minimum order quantity: 1 unit of 50uL

Furthermore, the high-risk groups of leukemia-free survival shorter (LFS) and overall survival (OS) of the low-risk group (P = 0.026; P = 0.006), and the signature of the three genes are prognostic a factor . three gene signatures for predicting prognosis in AML may serve as a prognostic biomarker.